Registered Nurses Salary in South Carolina: $82,360 Median Pay (May 2025 estimates)

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Median annual pay

$82,360 / year

15.6% below the national median

$42.15

Mean hourly wage

$87,670

Mean annual wage

49,750

Jobs in South Carolina

$39.60

Median hourly wage

Registered Nurses pay in South Carolina: the full picture

Registered Nurses in South Carolina earn a median of $82,360 per year ($39.60 per hour), based on May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics. The mean annual wage is $87,670, across an estimated 49,750 jobs. That puts South Carolina 15.6% below the national median of $97,550 for registered nurses.

Measure	Pay
Mean hourly wage	$42.15
Median annual wage	$82,360
Mean annual wage	$87,670
Median hourly wage	$39.60
Total employment	49,750

How South Carolina compares

Median annual pay for registered nurses across the areas we track. The national median is included for reference.

South Carolina

$82,360

San Jose

$216,740

San Francisco

$186,610

California

$140,270

Hawaii

$136,320

Frequently asked questions

How much does a RN make in South Carolina?

The median annual wage is $82,360 ($39.60/hour). The mean is $87,670 per year.

Is South Carolina a good place for registered nurses pay-wise?

South Carolina pays 15.6% below the national median ($97,550), with about 49,750 jobs in the area.

Where does this data come from?

All figures are May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), retrieved 2026-10-09. They are survey estimates, not job offers.

Keep exploring

More Registered Nurses salary data and other nursing roles in South Carolina.

Sources & methodology. All figures on this page come from the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates (released April 2026), retrieved 2026-10-09. "Median" is the 50th percentile — half of workers earn more, half earn less. "Mean" is the arithmetic average. Annual figures assume full-time, year-round work (2,080 hours). Employment estimates exclude the self-employed. Figures are rounded survey estimates, not job offers — actual pay varies by employer, shift, experience, and certifications.