Nurse Practitioners Salary in South Carolina: $123,290 Median Pay (May 2025 estimates)

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Median annual pay

$123,290 / year

6.8% below the national median

$59.70

Mean hourly wage

$124,170

Mean annual wage

5,670

Jobs in South Carolina

$59.28

Median hourly wage

Nurse Practitioners pay in South Carolina: the full picture

Nurse Practitioners in South Carolina earn a median of $123,290 per year ($59.28 per hour), based on May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics. The mean annual wage is $124,170, across an estimated 5,670 jobs. That puts South Carolina 6.8% below the national median of $132,300 for nurse practitioners.

Measure	Pay
Mean hourly wage	$59.70
Median annual wage	$123,290
Mean annual wage	$124,170
Median hourly wage	$59.28
Total employment	5,670

How South Carolina compares

Median annual pay for nurse practitioners across the areas we track. The national median is included for reference.

South Carolina

$123,290

San Jose

$231,560

San Francisco

$219,080

California

$168,520

New York City

$163,340

Frequently asked questions

How much does a NP make in South Carolina?

The median annual wage is $123,290 ($59.28/hour). The mean is $124,170 per year.

Is South Carolina a good place for nurse practitioners pay-wise?

South Carolina pays 6.8% below the national median ($132,300), with about 5,670 jobs in the area.

Where does this data come from?

All figures are May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), retrieved 2026-10-09. They are survey estimates, not job offers.

Keep exploring

More Nurse Practitioners salary data and other nursing roles in South Carolina.

Sources & methodology. All figures on this page come from the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates (released April 2026), retrieved 2026-10-09. "Median" is the 50th percentile — half of workers earn more, half earn less. "Mean" is the arithmetic average. Annual figures assume full-time, year-round work (2,080 hours). Employment estimates exclude the self-employed. Figures are rounded survey estimates, not job offers — actual pay varies by employer, shift, experience, and certifications.