Median annual pay
$129,930 / year
1.8% below the national median
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Nurse Practitioners pay in Missouri: the full picture
Nurse Practitioners in Missouri earn a median of $129,930 per year ($62.47 per hour), based on May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics. The mean annual wage is $130,970, across an estimated 7,710 jobs. That puts Missouri 1.8% below the national median of $132,300 for nurse practitioners.
| Measure | Pay |
|---|
| Mean hourly wage | $62.97 |
| Median annual wage | $129,930 |
| Mean annual wage | $130,970 |
| Median hourly wage | $62.47 |
| Total employment | 7,710 |
How Missouri compares
Median annual pay for nurse practitioners across the areas we track. The national median is included for reference.
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Frequently asked questions
How much does a NP make in Missouri?
The median annual wage is $129,930 ($62.47/hour). The mean is $130,970 per year.
Is Missouri a good place for nurse practitioners pay-wise?
Missouri pays 1.8% below the national median ($132,300), with about 7,710 jobs in the area.
Where does this data come from?
All figures are May 2025 estimates (released April 2026) from the U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), retrieved 2026-10-09. They are survey estimates, not job offers.
Keep exploring
More Nurse Practitioners salary data and other nursing roles in Missouri.
Sources & methodology. All figures on this page come from the
U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates (released April 2026), retrieved 2026-10-09.
"Median" is the 50th percentile — half of workers earn more, half earn less.
"Mean" is the arithmetic average. Annual figures assume full-time, year-round work
(2,080 hours). Employment estimates exclude the self-employed. Figures are
rounded survey estimates, not job offers — actual pay varies by employer,
shift, experience, and certifications.